Translational medicine and drug discovery download

Translational medicine and drug discovery

Name: Translational medicine and drug discovery

File size: 262mb

Upload: 5.2.2017

Language: English

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Note, however, that it is possible that a genetic variant influences one but not the other such as association with a biomarker but not disease ; under this scenario, there is no causal relationship among all three target, biomarker, and disease. Almost half of the work is dedicated to core of drug discovery using a translational approach, the identification of appropriate targets and screening methods for the identification of compounds interacting with these targets. Phase II trials involve larger groups and aim to test dosing requirements and pharmacodynamic relationships in target patient populations.